PebRx

Personalized Brain Health Innovations

Advancing

Early Detection Tools

Delivering

Targeted Therapies

Providing

Personalized Brain Health Interventions

Our Mission

At PebRX, we empower individuals, particularly APOE ε4 carriers, with personalized brain health solutions to intervene in cognitive decline.

• Precision diagnostics

• Targeted therapeutics

We aim to preserve brain resilience, delay dementia, and improve neurological outcomes.

Our Vision

We envision a future where dementia is preventable, not inevitable. We empower at-risk individuals to protect cognitive health, prevent decline, and recover from brain injury—ensuring lifelong brain vitality by combining :

• Personalized medicine

• Advanced technology

• Evidence-based strategies

Our portfolio focuses on early detection, proactive intervention, and long-term prevention.

Imaging & Early Detection of Neurodegeneration

Developing imaging probes to measure metabolic function inside the blood brain barrier (BBB).
- A platform technology with applications for Alzheimer's and Traumatic Brain Injury (TBI).
- Potential as a diagnostic companion to personalized medicine and intervention.

AI-Driven Risk Prediction for Early Dementia Detection

Integrating AI and machine learning to develop predictive models for early dementia risk and progression.
Combining wearable sensor data with EMR insights, including genetics, biomarkers, and comorbidities.
Delivering personalized risk assessments to support clinical decision-making and enable proactive care.

Driving Drug Discovery for
Neuroinflammation

Developing brain-penetrant inhibitors to treat neuroinflammation in Alzheimer’s, Parkinson’s, stroke, and brain injuries.
Leveraging a structure-based drug discovery platform to identify potent, selective candidates with strong safety and Blood Brain Barrier penetration.
Advancing companion diagnostics to enable targeted therapies and improve clinical outcomes.